MOTS-c

Buy MOTS-c Peptide for sale in the UK from Archeus Karma Bio, a trusted supplier of high-quality research-grade peptides. MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring mitochondrial-derived peptide that plays a key role in cellular energy regulation, metabolic homeostasis, and stress adaptation. It is composed of 16 amino acids and directly influences AMPK activation, fat metabolism, and glucose utilization. MOTS-c is one of the most promising peptides in metabolic, longevity, and exercise physiology research due to its ability to enhance cellular resilience and mitochondrial efficiency. Each batch from Archeus Karma Bio is lab-tested and verified for ≥99% purity, ensuring reliability and reproducibility in scientific research.

Key Features of MOTS-c Peptide for Sale

• Vial Sizes: 10mg and 40mg per vial.
• Ultra-Pure Quality: Verified ≥99% purity by HPLC and Mass Spectrometry.
  Form: Lyophilized (freeze-dried) powder, intended strictly for laboratory research.
• Storage Instructions: Store between 2°C to 8°C (36 to 46°F), protected from light and moisture. After reconstitution, refrigerate and avoid multiple freeze-thaw cycles.
• Molecular Formula: C(84)H(139)N(25)O(26); molecular weight approximately 2170 Da.
• Mechanism: Activates AMPK (AMP-activated protein kinase) pathways, enhances mitochondrial biogenesis, and regulates cellular metabolism and insulin sensitivity.

 Scientific Overview: Mechanism & Research Applications

Mechanism of Action:

MOTS-c acts as a metabolic signaling peptide produced by mitochondrial DNA. It functions as a regulator of energy metabolism, transmitting signals from the mitochondria to the nucleus , a process known as mitochondrial-nuclear communication.

Once released into the cytoplasm, MOTS-c activates the AMPK pathway, which enhances glucose uptake, lipid oxidation, and mitochondrial respiration. This results in improved metabolic flexibility, cellular endurance, and stress tolerance under nutrient-deficient or oxidative conditions.

Key Research Findings Include:

• Glucose Homeostasis: Improves glucose tolerance and insulin sensitivity in experimental models.
• Fat Metabolism: Enhances lipid oxidation and reduces fat accumulation.
• Mitochondrial Biogenesis: Promotes new mitochondrial formation, improving cellular energy output.
• Exercise Physiology: Boosts endurance, stamina, and recovery through enhanced muscle energy regulation.
• Longevity Research: Associated with improved metabolic health and delayed age-related decline in animal studies.
• Cellular Protection: Increases resistance to oxidative and metabolic stress.