5-Amino-1MQ 10mg
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5-Amino-1MQ is a powerful small molecule that inhibits the enzyme NNMT, a key player in fat tissue metabolism. By blocking NNMT, it boosts NAD+ levels, enhances metabolic rate, and activates the longevity-associated gene SIRT1.
26 in stock
All Instrips products are manufactured in cGMP-compliant facilities with strict adherence to quality standards. Full chain-of-custody documentation ensures traceability, reliability, and reproducibility for research purposes.
Designed for precision research, these peptides support a wide range of experimental protocols. Ideal for laboratory studies requiring consistent, reproducible compound delivery.
All products are intended for research use only. Follow standard lab safety guidelines, including proper protective equipment and waste disposal protocols.
5-Amino-1MQ is an advanced metabolic enhancer designed to support fat loss, optimize energy metabolism, and promote cellular longevity. This small molecule functions by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT)—a critical regulator of energy balance and fat cell function predominantly active in adipose (fat) tissue. By targeting NNMT, 5-Amino-1MQ unlocks a cascade of metabolic benefits that may contribute to better body composition and long-term health.
Mechanism of Action
At the core of its action, 5-Amino-1MQ blocks NNMT, leading to an increase in nicotinamide adenine dinucleotide (NAD+)—a coenzyme essential for cellular energy production and mitochondrial function. Elevated NAD+ levels stimulate SIRT1 (sirtuin-1), commonly referred to as the “longevity gene.” SIRT1 plays a vital role in improving insulin sensitivity, reducing inflammation, and protecting cells from age-related damage.
Benefits
- Supports Fat Loss: Research in mice demonstrated a 7% reduction in body mass over just 10 days with 5-Amino-1MQ administration, despite no changes in food intake. This suggests a direct role in fat metabolism and energy expenditure.
- Improves Metabolic Health: By modulating NAD+ and SIRT1, 5-Amino-1MQ may help regulate blood sugar, reduce fat accumulation, and combat metabolic syndrome.
- Activates Longevity Pathways: SIRT1 activation is associated with decreased risks of diabetes, cardiovascular disease, neurodegeneration, kidney and liver dysfunction, and certain cancers.
- Shrinks Fat Deposits: Studies show that inhibiting NNMT may help reduce the size of fat cells and minimize fat storage in tissues.
Scientific Background
NNMT is overexpressed in fat cells of obese individuals and has been linked to decreased energy expenditure. By reducing NNMT activity, 5-Amino-1MQ may shift the body’s metabolic programming toward increased calorie burning and improved mitochondrial health. Its unique approach makes it a promising candidate for combating obesity and age-related metabolic decline.
Applications
5-Amino-1MQ is currently studied for its potential in:
- Weight management programs
- Anti-aging and longevity support
- Metabolic syndrome and insulin resistance improvement
- Enhancing NAD+ levels and mitochondrial function
Certificate of Analysis (COA)
All Archeus Karma Bio products may be accompanied by a Certificate of Analysis (COA) where available. The COA provides verified laboratory testing information to confirm product identity, purity, and batch consistency.
Each COA is linked to a specific batch and is intended to support transparency and quality assurance for research purposes. Customers are encouraged to review COA documentation before use to ensure suitability for their scientific applications.
COA information is provided strictly for research reference and does not constitute medical or usage advice.
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